Mobilized mercury in subjects with varying exposure to elemental mercury vapour.
Identifieur interne : 000646 ( Main/Exploration ); précédent : 000645; suivant : 000647Mobilized mercury in subjects with varying exposure to elemental mercury vapour.
Auteurs : M. Molin [Suède] ; A. Schütz ; S. Skerfving ; G. S LlstenSource :
- International archives of occupational and environmental health [ 0340-0131 ] ; 1991.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Analyse de variance (MeSH), Exposition professionnelle (MeSH), Humains (MeSH), Mercure (sang), Mercure (urine), Mâle (MeSH), Polluants atmosphériques d'origine professionnelle (sang), Polluants atmosphériques d'origine professionnelle (urine), Unithiol (pharmacologie), Érythrocytes (métabolisme).
- MESH :
- métabolisme : Érythrocytes.
- pharmacologie : Unithiol.
- sang : Mercure, Polluants atmosphériques d'origine professionnelle.
- urine : Mercure, Polluants atmosphériques d'origine professionnelle.
- Adulte, Adulte d'âge moyen, Analyse de variance, Exposition professionnelle, Humains, Mâle.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Air Pollutants, Occupational, Mercury.
- chemical , pharmacology : Unithiol.
- chemical , urine : Air Pollutants, Occupational, Mercury.
- metabolism : Erythrocytes.
- Adult, Analysis of Variance, Humans, Male, Middle Aged, Occupational Exposure.
Abstract
In a mercury mobilization test, 0.3 g of the complexing agent sodium 2,3-dimercaptopropane-1-sulfonate (DMPS) was given orally to 10 workers with moderate occupational exposure to elemental mercury vapour, to 8 dentists with slight exposure, to 18 matched controls, and to 5 referents without amalgam fillings. In the workers, DMPS caused an increase in 24-h urinary mercury excretion by a factor of 10; in the dentists, 5.9; in the controls, 5.3; and in the amalgam-free referents, 3.8. Of the mercury excreted during 24 h, 59% appeared during the first 6 h. Close, albeit non-linear, associations were found between mobilized mercury and the premobilization mercury levels in plasma and urine, but not with the duration of occupational exposure or the rough estimate of the integrated function of blood levels vs time. The present data indicate that mercury mobilized after a single DMPS dose in close connection with exposure is mainly an index of recent exposure and is not significantly affected by slow body pools or long-term exposure.
DOI: 10.1007/BF00381567
PubMed: 1917069
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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S Llsten</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1991">1991</date><idno type="RBID">pubmed:1917069</idno><idno type="pmid">1917069</idno><idno type="doi">10.1007/BF00381567</idno><idno type="wicri:Area/Main/Corpus">000647</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000647</idno><idno type="wicri:Area/Main/Curation">000647</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000647</idno><idno type="wicri:Area/Main/Exploration">000647</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mobilized mercury in subjects with varying exposure to elemental mercury vapour.</title><author><name sortKey="Molin, M" sort="Molin, M" uniqKey="Molin M" first="M" last="Molin">M. Molin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Prosthetic Dentistry, University of Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Prosthetic Dentistry, University of Umeå</wicri:regionArea><wicri:noRegion>University of Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Schutz, A" sort="Schutz, A" uniqKey="Schutz A" first="A" last="Schütz">A. Schütz</name></author><author><name sortKey="Skerfving, S" sort="Skerfving, S" uniqKey="Skerfving S" first="S" last="Skerfving">S. Skerfving</name></author><author><name sortKey="S Llsten, G" sort="S Llsten, G" uniqKey="S Llsten G" first="G" last="S Llsten">G. S Llsten</name></author></analytic><series><title level="j">International archives of occupational and environmental health</title><idno type="ISSN">0340-0131</idno><imprint><date when="1991" type="published">1991</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Air Pollutants, Occupational (blood)</term><term>Air Pollutants, Occupational (urine)</term><term>Analysis of Variance (MeSH)</term><term>Erythrocytes (metabolism)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Mercury (blood)</term><term>Mercury (urine)</term><term>Middle Aged (MeSH)</term><term>Occupational Exposure (MeSH)</term><term>Unithiol (pharmacology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Analyse de variance (MeSH)</term><term>Exposition professionnelle (MeSH)</term><term>Humains (MeSH)</term><term>Mercure (sang)</term><term>Mercure (urine)</term><term>Mâle (MeSH)</term><term>Polluants atmosphériques d'origine professionnelle (sang)</term><term>Polluants atmosphériques d'origine professionnelle (urine)</term><term>Unithiol (pharmacologie)</term><term>Érythrocytes (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Air Pollutants, Occupational</term><term>Mercury</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Unithiol</term></keywords><keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Air Pollutants, Occupational</term><term>Mercury</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Erythrocytes</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Érythrocytes</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Unithiol</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Mercure</term><term>Polluants atmosphériques d'origine professionnelle</term></keywords><keywords scheme="MESH" qualifier="urine" xml:lang="fr"><term>Mercure</term><term>Polluants atmosphériques d'origine professionnelle</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Analysis of Variance</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Occupational Exposure</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de variance</term><term>Exposition professionnelle</term><term>Humains</term><term>Mâle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In a mercury mobilization test, 0.3 g of the complexing agent sodium 2,3-dimercaptopropane-1-sulfonate (DMPS) was given orally to 10 workers with moderate occupational exposure to elemental mercury vapour, to 8 dentists with slight exposure, to 18 matched controls, and to 5 referents without amalgam fillings. In the workers, DMPS caused an increase in 24-h urinary mercury excretion by a factor of 10; in the dentists, 5.9; in the controls, 5.3; and in the amalgam-free referents, 3.8. Of the mercury excreted during 24 h, 59% appeared during the first 6 h. Close, albeit non-linear, associations were found between mobilized mercury and the premobilization mercury levels in plasma and urine, but not with the duration of occupational exposure or the rough estimate of the integrated function of blood levels vs time. The present data indicate that mercury mobilized after a single DMPS dose in close connection with exposure is mainly an index of recent exposure and is not significantly affected by slow body pools or long-term exposure.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">1917069</PMID><DateCompleted><Year>1991</Year><Month>11</Month><Day>14</Day></DateCompleted><DateRevised><Year>2019</Year><Month>09</Month><Day>07</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0340-0131</ISSN><JournalIssue CitedMedium="Print"><Volume>63</Volume><Issue>3</Issue><PubDate><Year>1991</Year></PubDate></JournalIssue><Title>International archives of occupational and environmental health</Title><ISOAbbreviation>Int Arch Occup Environ Health</ISOAbbreviation></Journal><ArticleTitle>Mobilized mercury in subjects with varying exposure to elemental mercury vapour.</ArticleTitle><Pagination><MedlinePgn>187-92</MedlinePgn></Pagination><Abstract><AbstractText>In a mercury mobilization test, 0.3 g of the complexing agent sodium 2,3-dimercaptopropane-1-sulfonate (DMPS) was given orally to 10 workers with moderate occupational exposure to elemental mercury vapour, to 8 dentists with slight exposure, to 18 matched controls, and to 5 referents without amalgam fillings. In the workers, DMPS caused an increase in 24-h urinary mercury excretion by a factor of 10; in the dentists, 5.9; in the controls, 5.3; and in the amalgam-free referents, 3.8. Of the mercury excreted during 24 h, 59% appeared during the first 6 h. Close, albeit non-linear, associations were found between mobilized mercury and the premobilization mercury levels in plasma and urine, but not with the duration of occupational exposure or the rough estimate of the integrated function of blood levels vs time. The present data indicate that mercury mobilized after a single DMPS dose in close connection with exposure is mainly an index of recent exposure and is not significantly affected by slow body pools or long-term exposure.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Molin</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Prosthetic Dentistry, University of Umeå, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schütz</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Skerfving</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Sällsten</LastName><ForeName>G</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Int Arch Occup Environ Health</MedlineTA><NlmUniqueID>7512134</NlmUniqueID><ISSNLinking>0340-0131</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000395">Air Pollutants, Occupational</NameOfSubstance></Chemical><Chemical><RegistryNumber>4076-02-2</RegistryNumber><NameOfSubstance UI="D014494">Unithiol</NameOfSubstance></Chemical><Chemical><RegistryNumber>FXS1BY2PGL</RegistryNumber><NameOfSubstance UI="D008628">Mercury</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000395" MajorTopicYN="N">Air Pollutants, Occupational</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000652" MajorTopicYN="Y">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004912" MajorTopicYN="N">Erythrocytes</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008628" MajorTopicYN="N">Mercury</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000652" MajorTopicYN="Y">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="N">Occupational Exposure</DescriptorName></MeshHeading><MeshHeading><DescriptorName 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S Llsten</name><name sortKey="Schutz, A" sort="Schutz, A" uniqKey="Schutz A" first="A" last="Schütz">A. Schütz</name><name sortKey="Skerfving, S" sort="Skerfving, S" uniqKey="Skerfving S" first="S" last="Skerfving">S. Skerfving</name></noCountry><country name="Suède"><noRegion><name sortKey="Molin, M" sort="Molin, M" uniqKey="Molin M" first="M" last="Molin">M. Molin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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